No, it is not wise to microdose if you use antibiotics. Your brain contains many neurons, which communicate through synapses. If you combine medicines and microdosings, the combination can be disrupted by stimuli and damping. This has to do with the neurotransmitters that are active. In addition, your immune system can respond to the use of microdosings. That may mean that you feel warm, sick or poor.
Different combinations will not stand in the way. Always consult a doctor if you think of microdosing, while using antibiotics or other medicines. Moreover, it is a good idea to drink enough water if you want microdos.